American biotechnology company that produces gene-edited pig organs for xenotransplantation through its subsidiary Revivicor. The company received FDA permission in 2025 to begin clinical trials of pig kidneys.
United Therapeutics has performed two pig-heart transplants and has permission to test its "UThymoKidney", which combines a pig kidney with porcine thymus tissue. The thymus is a gland that helps train the immune system to distinguish threats from the body's own cells; the hope is that a combination transplant will encourage the recipient's immune system to tolerate the new kidney.
The company is testing ravulizumab, a drug already prescribed for autoimmune disorders, as a post-transplant treatment.
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